BDBM50239869 CHEMBL4084949

SMILES O=C1Nc2cc(=O)n(Cc3ccccc3)cc2CN1c1cccc(OCc2cncs2)c1

InChI Key InChIKey=GAWVULNDIBAUHU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50239869   

TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239869(CHEMBL4084949)
Affinity DataIC50:  79nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239869(CHEMBL4084949)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239869(CHEMBL4084949)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239869(CHEMBL4084949)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 helicase activity expressed in baculovirus infected Sf9 cells assessed as redu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase DHX29(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239869(CHEMBL4084949)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length recombinant human N-terminal FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed