BDBM50240115 CHEMBL4070891

SMILES COc1ccc(C(=O)N[C@H](COc2ccc(/C=C/C(=O)NO)cc2OC)Cc2c[nH]c3ccccc23)cc1

InChI Key InChIKey=RJLOHWUSSDUKRN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240115   

TargetHistone deacetylase 3(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240115BDBM50240115(CHEMBL4070891)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of HDAC3 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240115BDBM50240115(CHEMBL4070891)
Affinity DataIC50: 18nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240115BDBM50240115(CHEMBL4070891)
Affinity DataIC50: 60nMAssay Description:Inhibition of HDAC2 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240115BDBM50240115(CHEMBL4070891)
Affinity DataIC50: 87nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details Article
PubMed