BDBM50240784 CHEMBL4076118

SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1cccc(F)c1O

InChI Key InChIKey=VVMFTDMSORZANW-VWLOTQADSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240784   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240784(CHEMBL4076118)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of recombinant human FGFR2 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240784(CHEMBL4076118)
Affinity DataIC50:  294nMAssay Description:Compound was tested for binding affinity to Serotonin transporter sites in homogenates prepared from rat cortical membranes using [3H]paroxetine as r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240784(CHEMBL4076118)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240784(CHEMBL4076118)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant human FGFR3 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed