BDBM50240790 CHEMBL4082721

SMILES Cc1n[nH]c2ncc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1cc(Cl)ccc1O

InChI Key InChIKey=OCAAZMTTXWHARF-QHCPKHFHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240790   

TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240790(CHEMBL4082721)
Affinity DataIC50:  94nMAssay Description:Inhibition of recombinant human FGFR3 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240790(CHEMBL4082721)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of recombinant human FGFR2 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240790(CHEMBL4082721)
Affinity DataIC50:  2.28E+3nMAssay Description:Inhibition of FGFR2 in human SNU16 cells assessed as inhibition of cell proliferation after 72 hrs by cell counting kit-8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240790(CHEMBL4082721)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed