BDBM50240800 CHEMBL4074407

SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1cc(F)c(F)cc1O

InChI Key InChIKey=CNKVGRHQVUWEFQ-VWLOTQADSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240800   

TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240800(CHEMBL4074407)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant human FGFR3 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240800(CHEMBL4074407)
Affinity DataIC50:  289nMAssay Description:Inhibition of FGFR2 in human SNU16 cells assessed as inhibition of cell proliferation after 72 hrs by cell counting kit-8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240800(CHEMBL4074407)
Affinity DataIC50:  2.80nMAssay Description:In vitro inhibition of HMG-CoA reductase in solubilized rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240800(CHEMBL4074407)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed