BDBM50240967 CHEMBL4090181

SMILES Cl.Oc1cccc(CCN(CCc2ccccc2)CC2CCC2)c1F

InChI Key InChIKey=RDNHNYSGWSGOCV-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240967   

TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50240967(CHEMBL4090181)
Affinity DataKi:  0.0720nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50240967(CHEMBL4090181)
Affinity DataKi:  398nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50240967(CHEMBL4090181)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50240967(CHEMBL4090181)
Affinity DataEC50:  6.90nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed