BDBM50241184 (E)-N-(1-(2-(1H-indol-3-yl)ethylamino)-2-methyl-1-oxopropan-2-yl)-3-(4-methoxyphenyl)acrylamide::CHEMBL397044::N-(1-(2-(1H-indol-3-yl)ethylamino)-2-methyl-1-oxopropan-2-yl)-3-(4-methoxyphenyl)acrylamide

SMILES COc1ccc(\C=C\C(=O)NC(C)(C)C(=O)NCCc2c[nH]c3ccccc23)cc1

InChI Key InChIKey=NFTZRUIUOHRXTH-JLHYYAGUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241184   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50241184((E)-N-(1-(2-(1H-indol-3-yl)ethylamino)-2-methyl-1-...)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibition of SIRT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50241184((E)-N-(1-(2-(1H-indol-3-yl)ethylamino)-2-methyl-1-...)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibition of recombinant GST-tagged SIRT2 (unknown origin) by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed