BDBM50242456 CHEMBL4104533

SMILES Fc1ccc2n(CC(=O)NCc3nc4ccccc4[nH]3)c(cc2c1)-c1ncco1

InChI Key InChIKey=VERHZRWOVSXMOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242456   

LigandPNGBDBM50242456(CHEMBL4104533)
Affinity DataIC50: 113nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50242456(CHEMBL4104533)
Affinity DataIC50: 6.88E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed