BDBM50242899 (2S,3S)-2-(3-(4-fluorophenyl)isoxazol-5-yl)-8-methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane hydrochloride::CHEMBL470903

SMILES CN1C2CCC1[C@H]([C@H](C2)c1ccc(C)cc1)c1cc(no1)-c1ccc(F)cc1

InChI Key InChIKey=HDJDHOXJDMHXTD-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50242899   

TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50242899((2S,3S)-2-(3-(4-fluorophenyl)isoxazol-5-yl)-8-meth...)
Affinity DataIC50: 6.45nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50242899((2S,3S)-2-(3-(4-fluorophenyl)isoxazol-5-yl)-8-meth...)
Affinity DataKi:  552nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50242899((2S,3S)-2-(3-(4-fluorophenyl)isoxazol-5-yl)-8-meth...)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed