BDBM50242924 4-methyl-N3-(pyrimidin-5-yl)-N1-(3-(trifluoromethyl)phenyl)isophthalamide::CHEMBL512840

SMILES Cc1ccc(cc1C(=O)Nc1cncnc1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=RITKUWAOEQBXTJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50242924   

LigandPNGBDBM50242924(4-methyl-N3-(pyrimidin-5-yl)-N1-(3-(trifluoromethy...)
Affinity DataIC50: 37nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50242924(4-methyl-N3-(pyrimidin-5-yl)-N1-(3-(trifluoromethy...)
Affinity DataIC50: 546nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50242924(4-methyl-N3-(pyrimidin-5-yl)-N1-(3-(trifluoromethy...)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50242924(4-methyl-N3-(pyrimidin-5-yl)-N1-(3-(trifluoromethy...)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50242924(4-methyl-N3-(pyrimidin-5-yl)-N1-(3-(trifluoromethy...)
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed