BDBM50242986 (2S,3S)-3-(4-chlorophenyl)-2-(3-(4-methoxyphenyl)isoxazol-5-yl)-8-methyl-8-aza-bicyclo[3.2.1]octane hydrochloride::CHEMBL469887

SMILES COc1ccc(cc1)-c1cc(on1)[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)cc1)N2C

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50242986   

TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50242986((2S,3S)-3-(4-chlorophenyl)-2-(3-(4-methoxyphenyl)i...)
Affinity DataIC50: 1.57nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50242986((2S,3S)-3-(4-chlorophenyl)-2-(3-(4-methoxyphenyl)i...)
Affinity DataKi:  454nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50242986((2S,3S)-3-(4-chlorophenyl)-2-(3-(4-methoxyphenyl)i...)
Affinity DataKi:  535nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed