BDBM50242991 3beta-(4-chlorophenyl)-2beta-[3'-methyl-4'-(4-methoxyphenyl)isoxazol-5-yl]tropanehydrochloride::CHEMBL470488

SMILES COc1ccc(cc1)-c1c(C)noc1[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)cc1)N2C

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50242991   

TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50242991(3beta-(4-chlorophenyl)-2beta-[3'-methyl-4'-(4-meth...)
Affinity DataIC50: 81.6nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50242991(3beta-(4-chlorophenyl)-2beta-[3'-methyl-4'-(4-meth...)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50242991(3beta-(4-chlorophenyl)-2beta-[3'-methyl-4'-(4-meth...)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed