BDBM50243038 CHEMBL4092752

SMILES COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3cc4cnccc4o3)C(=O)c2c1

InChI Key InChIKey=QOWBVKQSFCSJAK-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50243038   

LigandPNGBDBM50243038(CHEMBL4092752)
Affinity DataKi:  0.700nMAssay Description:Inhibition of catalytic domain TACE (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
LigandPNGBDBM50243038(CHEMBL4092752)
Affinity DataIC50: 144nMAssay Description:Inhibition of ADAM10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50243038(CHEMBL4092752)
Affinity DataIC50: 239nMAssay Description:Inhibition of MMP14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50243038(CHEMBL4092752)
Affinity DataIC50: 533nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50243038(CHEMBL4092752)
Affinity DataIC50: 684nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50243038(CHEMBL4092752)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50243038(CHEMBL4092752)
Affinity DataIC50: 4.71E+3nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50243038(CHEMBL4092752)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetMatrilysin(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50243038(CHEMBL4092752)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of MMP7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed