BDBM50243074 CHEMBL469882::N-(2-methyl-5-((3-(trifluoromethyl)phenyl)carbamoyl)phenyl)pyrimidine-5-carboxamide

SMILES Cc1ccc(cc1NC(=O)c1cncnc1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=SJHUSHHZUDUTHB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50243074   

LigandPNGBDBM50243074(N-(2-methyl-5-((3-(trifluoromethyl)phenyl)carbamoy...)
Affinity DataIC50: 108nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50243074(N-(2-methyl-5-((3-(trifluoromethyl)phenyl)carbamoy...)
Affinity DataIC50: 455nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50243074(N-(2-methyl-5-((3-(trifluoromethyl)phenyl)carbamoy...)
Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50243074(N-(2-methyl-5-((3-(trifluoromethyl)phenyl)carbamoy...)
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50243074(N-(2-methyl-5-((3-(trifluoromethyl)phenyl)carbamoy...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed