BDBM50243076 CHEMBL470483::N3-(6-aminopyridin-3-yl)-4-methyl-N1-(3-(trifluoromethyl)phenyl)isophthalamide

SMILES Cc1ccc(cc1C(=O)Nc1ccc(N)nc1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=MAXWPKHIRAUGLM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243076   

LigandPNGBDBM50243076(CHEMBL470483 | N3-(6-aminopyridin-3-yl)-4-methyl-N...)
Affinity DataIC50:  470nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50243076(CHEMBL470483 | N3-(6-aminopyridin-3-yl)-4-methyl-N...)
Affinity DataIC50:  7nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50243076(CHEMBL470483 | N3-(6-aminopyridin-3-yl)-4-methyl-N...)
Affinity DataIC50:  24nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed