BDBM50243138 3beta-(4-Chlorophenyl)-2beta-[3'-(4-fluorobenzyl)isoxazol-5-yl]-tropane hydrochloride::CHEMBL488423

SMILES CN1C2CCC1[C@H]([C@H](C2)c1ccc(Cl)cc1)c1cc(Cc2ccc(F)cc2)no1

InChI Key InChIKey=LXNFWMBEBKFFDO-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243138   

TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50243138(3beta-(4-Chlorophenyl)-2beta-[3'-(4-fluorobenzyl)i...)
Affinity DataIC50: 8.60nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50243138(3beta-(4-Chlorophenyl)-2beta-[3'-(4-fluorobenzyl)i...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50243138(3beta-(4-Chlorophenyl)-2beta-[3'-(4-fluorobenzyl)i...)
Affinity DataKi:  435nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed