BDBM50243180 CHEMBL488834::N3-(6-aminopyridin-3-yl)-N1-(2-cyclohexylethyl)-4-methylisophthalamide

SMILES Cc1ccc(cc1C(=O)Nc1ccc(N)nc1)C(=O)NCCC1CCCCC1

InChI Key InChIKey=WKRGWNGOAPQILF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243180   

LigandPNGBDBM50243180(N3-(6-aminopyridin-3-yl)-N1-(2-cyclohexylethyl)-4-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50243180(N3-(6-aminopyridin-3-yl)-N1-(2-cyclohexylethyl)-4-...)
Affinity DataIC50: 181nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50243180(N3-(6-aminopyridin-3-yl)-N1-(2-cyclohexylethyl)-4-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed