BDBM50243191 3beta-(4-Chlorophenyl)-2beta-[3'-(4-methoxybenzyl)isoxazol-5-yl]-tropane hydrochloride::CHEMBL487874

SMILES COc1ccc(Cc2cc(on2)[C@@H]2C3CCC(C[C@@H]2c2ccc(Cl)cc2)N3C)cc1

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243191   

TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50243191(3beta-(4-Chlorophenyl)-2beta-[3'-(4-methoxybenzyl)...)
Affinity DataIC50: 6.10nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50243191(3beta-(4-Chlorophenyl)-2beta-[3'-(4-methoxybenzyl)...)
Affinity DataKi:  14.4nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50243191(3beta-(4-Chlorophenyl)-2beta-[3'-(4-methoxybenzyl)...)
Affinity DataKi:  347nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed