BDBM50243209 CHEMBL486044::trans-N-methyl-3-(o-tolyloxy)-2,3-dihydro-1H-inden-1-amine

SMILES CN[C@H]1C[C@H](Oc2ccccc2C)c2ccccc12

InChI Key InChIKey=WPKZZLMFEYGCJR-RDJZCZTQSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243209   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243209(CHEMBL486044 | trans-N-methyl-3-(o-tolyloxy)-2,3-d...)
Affinity DataIC50:  180nMAssay Description:Inhibition of dopamine uptake at human DAT in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243209(CHEMBL486044 | trans-N-methyl-3-(o-tolyloxy)-2,3-d...)
Affinity DataIC50:  370nMAssay Description:Inhibition of serotonin uptake at human SERT in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243209(CHEMBL486044 | trans-N-methyl-3-(o-tolyloxy)-2,3-d...)
Affinity DataIC50:  72nMAssay Description:Inhibition of norepinephrine uptake at human NET in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed