BDBM50243270 CHEMBL447598::cis-N-methyl-4-(o-tolyloxy)-1,2,3,4-tetrahydronaphthalen-1-amine

SMILES CN[C@@H]1CC[C@H](Oc2ccccc2C)c2ccccc12

InChI Key InChIKey=RFOPOIPYLVKPSZ-AEFFLSMTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243270   

TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243270(CHEMBL447598 | cis-N-methyl-4-(o-tolyloxy)-1,2,3,4...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of dopamine uptake at human DAT in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243270(CHEMBL447598 | cis-N-methyl-4-(o-tolyloxy)-1,2,3,4...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of serotonin uptake at human SERT in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243270(CHEMBL447598 | cis-N-methyl-4-(o-tolyloxy)-1,2,3,4...)
Affinity DataIC50:  520nMAssay Description:Inhibition of norepinephrine uptake at human NET in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed