BDBM50243354 (S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-2-(thiophen-2-yl)acetic acid::CHEMBL452278

SMILES Cc1cccc(Cl)c1NC(=O)Nc1cc2ccccc2cc1C(=O)N[C@@H](C(O)=O)c1cccs1

InChI Key InChIKey=LSETZGXFLJVLBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243354   

TargetGlycogen phosphorylase, liver form(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243354((S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-nap...)
Affinity DataIC50: 360nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243354((S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-nap...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human glycogen phosphorylase alpha in HepG2 cells assessed as inhibition of forskolin-induced glycogenolysis after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed