BDBM50243595 (S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)-Nethylbenzamide::CHEMBL461292

SMILES CCN(C1CCCCC1)C(=O)c1ccc(cc1)[C@](C)(O)C(F)(F)F

InChI Key InChIKey=WLWHNXMTVCKXGI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243595   

LigandPNGBDBM50243595((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243595((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human cloned 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243595((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed