BDBM50243631 CHEMBL444567::N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)-N-cyclopropylmethylbenzamide

SMILES CC(O)(c1ccc(cc1)C(=O)N(CC1CC1)C1CCCCC1)C(F)(F)F

InChI Key InChIKey=LZPTUQPRKHRPEL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243631   

LigandPNGBDBM50243631(N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropan-2-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human cloned 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243631(N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropan-2-...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243631(N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropan-2-...)
Affinity DataIC50: 849nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed