BDBM50243897 CHEMBL488640::N-Cycloheptyl-2-[4-(dimethylamino)piperidine-1-yl]-6,7-dimethoxyquinazolin-4-amine

SMILES COc1cc2nc(nc(NC3CCCCCC3)c2cc1OC)N1CCC(CC1)N(C)C

InChI Key InChIKey=XWMACLNQDPPMDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243897   

TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243897(N-Cycloheptyl-2-[4-(dimethylamino)piperidine-1-yl]...)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243897(N-Cycloheptyl-2-[4-(dimethylamino)piperidine-1-yl]...)
Affinity DataIC50: 730nMAssay Description:Displacement of [125I]CCl22 from human CCR4 receptor expressed in mouse B300-19 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed