BDBM50244222 4-(Benzylamino)-2-{[4-(3-hydroxypyrrolidine-1-yl)phenyl]amino}pyrimidine-5-carboxamide::CHEMBL458325

SMILES NC(=O)c1cnc(Nc2ccc(cc2)N2CCC(O)C2)nc1NCc1ccccc1

InChI Key InChIKey=XPFHFGPSTXPYCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244222   

TargetSignal transducer and activator of transcription 6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244222(4-(Benzylamino)-2-{[4-(3-hydroxypyrrolidine-1-yl)p...)
Affinity DataIC50: 98nMAssay Description:Inhibition of STAT6 activation in FW4 reporter cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed