BDBM50244300 CHEMBL470955::trans-4-(((4-tert-butylcyclohexyl)(1,5,6-trimethyl-1H-benzo[d]imidazol-2-yl)amino)methyl)-N-(1H-tetrazol-5-yl)benzamide

SMILES Cc1cc2nc(N(Cc3ccc(cc3)C(=O)Nc3nnn[nH]3)[C@H]3CC[C@@H](CC3)C(C)(C)C)n(C)c2cc1C

InChI Key InChIKey=GLRUMVHZMOEWPW-YHBQERECSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50244300   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244300(CHEMBL470955 | trans-4-(((4-tert-butylcyclohexyl)(...)
Affinity DataIC50:  18nMAssay Description:Antagonist activity against human GCGR expressed in CHO cells assessed as glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244300(CHEMBL470955 | trans-4-(((4-tert-butylcyclohexyl)(...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244300(CHEMBL470955 | trans-4-(((4-tert-butylcyclohexyl)(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity against human GIPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed