BDBM50244624 9-(2,6-dimethylstyryl)-N-(4-(dimethylphosphoryl)phenyl)-2-methoxy-9H-purin-6-amine::CHEMBL509002

SMILES COc1nc(Nc2ccc(cc2)P(C)(C)=O)c2ncn(\C=C\c3c(C)cccc3C)c2n1

InChI Key InChIKey=BWHGYXORZLZUIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244624   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50244624(9-(2,6-dimethylstyryl)-N-(4-(dimethylphosphoryl)ph...)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50244624(9-(2,6-dimethylstyryl)-N-(4-(dimethylphosphoryl)ph...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed