BDBM50244654 (S)-2-(3-((3-(4-chlorophenoxy)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)-4-fluorophenoxy)propanoic acid::CHEMBL509369

SMILES C[C@H](Oc1ccc(F)c(Cn2c(C)c(Oc3ccc(Cl)cc3)c3cccnc23)c1)C(O)=O

InChI Key InChIKey=GQNSETYZJHTWKU-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50244654   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244654((S)-2-(3-((3-(4-chlorophenoxy)-2-methyl-1H-pyrrolo...)
Affinity DataIC50: 54nMAssay Description:Displacement of [3H]2AD-5075 from GST-tagged human PPARgamma receptor expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244654((S)-2-(3-((3-(4-chlorophenoxy)-2-methyl-1H-pyrrolo...)
Affinity DataEC50:  156nMAssay Description:Agonist activity at human PPARgamma receptor expressed in african green monkey COS cells after 48 hrs by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244654((S)-2-(3-((3-(4-chlorophenoxy)-2-methyl-1H-pyrrolo...)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity to human PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244654((S)-2-(3-((3-(4-chlorophenoxy)-2-methyl-1H-pyrrolo...)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity to PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed