BDBM50245036 CHEMBL486840::N-(4-Chlorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1-ylpiperidin-1-yl)quinazolin-4-amine
SMILES COc1cc2nc(nc(Nc3ccc(Cl)cc3)c2cc1OC)N1CCC(CC1)N1CCCC1
InChI Key InChIKey=HGXZQFOHAJZQST-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50245036
Affinity DataIC50: 130nMAssay Description:Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Antagonist activity at human CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Displacement of [121I]CCL22 from human CCR4 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair