BDBM50245395 CHEMBL461998::N-[({5-[(6,7-Dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}amino)carbonyl]-2,6-difluorobenzamide

SMILES COc1cc2nccc(Oc3ccc(NC(=O)NC(=O)c4c(F)cccc4F)nc3)c2cc1OC

InChI Key InChIKey=YNVDGNMISSEEAV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245395   

TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245395(N-[({5-[(6,7-Dimethoxyquinolin-4-yl)oxy]pyridin-2-...)
Affinity DataKi:  80nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245395(N-[({5-[(6,7-Dimethoxyquinolin-4-yl)oxy]pyridin-2-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed