BDBM50245453 2-(3-chlorophenoxy)-N-(1-((1-(4-cyanophenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide::CHEMBL512180

SMILES Clc1cccc(OCC(=O)NC2CCN(Cc3ccn(c3)-c3ccc(cc3)C#N)CC2)c1

InChI Key InChIKey=ZOJCSYXNGZKDMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245453   

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50245453(2-(3-chlorophenoxy)-N-(1-((1-(4-cyanophenyl)-1H-py...)
Affinity DataIC50: 52nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50245453(2-(3-chlorophenoxy)-N-(1-((1-(4-cyanophenyl)-1H-py...)
Affinity DataIC50: 145nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed