BDBM50245603 CHEMBL4096207

SMILES Cc1c(NC(=O)c2cc3CCCCc3s2)cccc1-c1cc(Nc2ccc(C(=O)N3CCOCC3)c(NC(=O)C=C)c2)c(=O)n(C)c1

InChI Key InChIKey=UQDKCJOIUBVSRC-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50245603   

TargetTyrosine-protein kinase BTK(Human)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM50245603(CHEMBL4096207)
Affinity DataKi:  6nMAssay Description:Reversible inhibition of full length recombinant human N-terminal His tagged BKT expressed in baculovirus infected Sf9 insect cells using poly (Glu,T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM50245603(CHEMBL4096207)
Affinity DataIC50: 17nMAssay Description:Inhibition of full length recombinant human N-terminal His tagged BKT expressed in baculovirus infected Sf9 insect cells using poly (Glu,Tyr)4:1 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM50245603(CHEMBL4096207)
Affinity DataIC50: 341nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged BMX expressed in baculovirus infected Sf9 insect cells using poly (Glu,Tyr)4:1 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM50245603(CHEMBL4096207)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 insect cells using poly (Glu,T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM50245603(CHEMBL4096207)
Affinity DataIC50: 6.86E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged wild-type EGFR (695 to end residues) expressed in baculovirus infected Sf9 insect cells using p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed