BDBM50245852 CHEMBL458333::N3-(2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl)-N6-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine
SMILES COC(C)(C)CCn1nc(Nc2c(C)cccc2C)c2cnc(Nc3ccc(OCCN4CCCC4)cc3)nc12
InChI Key InChIKey=CAQLNQYCCKYWJX-UHFFFAOYSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50245852
Affinity DataKi: 0.0400nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of histidine-tagged ACK1 (amino acids 117 to 489) (unknown origin) expressed in SF9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of flag-tagged ACK1 (unknown origin) autophosphorylation expressed in human 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of Jak3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.16E+3nMAssay Description:Inhibition of Tie2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.59E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair