BDBM50245861 (R)-4-(3-(2,6-dimethylphenylamino)-6-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)butane-1,2-diol::CHEMBL461337

SMILES Cc1cccc(C)c1Nc1nn(CC[C@@H](O)CO)c2nc(Nc3ccccc3)ncc12

InChI Key InChIKey=QYPXYHBMOKMJRW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245861   

TargetActivated CDC42 kinase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50245861((R)-4-(3-(2,6-dimethylphenylamino)-6-(phenylamino)...)
Affinity DataKi:  30nMAssay Description:Inhibition of histidine-tagged ACK1 (amino acids 117 to 489) expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50245861((R)-4-(3-(2,6-dimethylphenylamino)-6-(phenylamino)...)
Affinity DataKi:  60nMAssay Description:Inhibition of flag-tagged ACK1 autophosphorylation expressed in human 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed