BDBM50245914 4-(2-(6-fluoro-3,4-dihydro-2H-chromen-3-yl)benzo[d]oxazol-6-yl)pyrimidin-2-amine::CHEMBL517561

SMILES Nc1nccc(n1)-c1ccc2nc(oc2c1)C1COc2ccc(F)cc2C1

InChI Key InChIKey=SKTFFJCCFCEJCG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245914   

TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute-Florida

Curated by ChEMBL
LigandPNGBDBM50245914(4-(2-(6-fluoro-3,4-dihydro-2H-chromen-3-yl)benzo[d...)
Affinity DataIC50: 15nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute-Florida

Curated by ChEMBL
LigandPNGBDBM50245914(4-(2-(6-fluoro-3,4-dihydro-2H-chromen-3-yl)benzo[d...)
Affinity DataIC50: 28nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed