BDBM50246217 2-(3-(2,6-dichlorophenylamino)-6-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-N,N-dimethylacetamide::CHEMBL488062

SMILES CN(C)C(=O)Cn1nc(Nc2c(Cl)cccc2Cl)c2cnc(Nc3ccccc3)nc12

InChI Key InChIKey=BNIPJOZBAQYAIO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246217   

TargetActivated CDC42 kinase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50246217(2-(3-(2,6-dichlorophenylamino)-6-(phenylamino)-1H-...)
Affinity DataKi:  30nMAssay Description:Inhibition of histidine-tagged ACK1 (amino acids 117 to 489) expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50246217(2-(3-(2,6-dichlorophenylamino)-6-(phenylamino)-1H-...)
Affinity DataKi:  90nMAssay Description:Inhibition of flag-tagged ACK1 autophosphorylation expressed in human 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed