BDBM50246262 1-(3-(dimethylamino)propyl)-N3-(2,6-dimethylphenyl)-N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine::CHEMBL521381

SMILES CN(C)CCCn1nc(Nc2c(C)cccc2C)c2cnc(Nc3ccccc3)nc12

InChI Key InChIKey=NCRTTXWMLNQNSD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246262   

TargetActivated CDC42 kinase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50246262(1-(3-(dimethylamino)propyl)-N3-(2,6-dimethylphenyl...)
Affinity DataKi:  30nMAssay Description:Inhibition of histidine-tagged ACK1 (amino acids 117 to 489) expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50246262(1-(3-(dimethylamino)propyl)-N3-(2,6-dimethylphenyl...)
Affinity DataKi:  40nMAssay Description:Inhibition of flag-tagged ACK1 autophosphorylation expressed in human 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed