BDBM50246372 4-(3,4-dichlorophenoxy)-3-((methylamino)methyl)benzonitrile::CHEMBL451076

SMILES CNCc1cc(ccc1Oc1ccc(Cl)c(Cl)c1)C#N

InChI Key InChIKey=ZPJJDPPFWWSPPB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50246372   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246372(4-(3,4-dichlorophenoxy)-3-((methylamino)methyl)ben...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of serotonin reuptake at SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246372(4-(3,4-dichlorophenoxy)-3-((methylamino)methyl)ben...)
Affinity DataIC50: 3.18E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50246372(4-(3,4-dichlorophenoxy)-3-((methylamino)methyl)ben...)
Affinity DataIC50: 4.56E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed