BDBM50246374 1-(2-(3,4-dichlorophenoxy)-4,5-dimethylphenyl)-N-methylmethanamine::CHEMBL455425

SMILES CNCc1cc(C)c(C)cc1Oc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=NPJYROQKHDJYRQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50246374   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246374(1-(2-(3,4-dichlorophenoxy)-4,5-dimethylphenyl)-N-m...)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of serotonin reuptake at SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246374(1-(2-(3,4-dichlorophenoxy)-4,5-dimethylphenyl)-N-m...)
Affinity DataIC50: 79.4nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50246374(1-(2-(3,4-dichlorophenoxy)-4,5-dimethylphenyl)-N-m...)
Affinity DataIC50: 1.48E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed