BDBM50246410 2-(3,4-dihydro-2H-chromen-3-yl)-6-(1H-pyrazol-4-yl)benzo[d]oxazole::CHEMBL509011

SMILES C1Oc2ccccc2CC1c1nc2ccc(cc2o1)-c1cn[nH]c1

InChI Key InChIKey=SZVIMUNJLGYDLN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246410   

TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute-Florida

Curated by ChEMBL
LigandPNGBDBM50246410(2-(3,4-dihydro-2H-chromen-3-yl)-6-(1H-pyrazol-4-yl...)
Affinity DataIC50: 21nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute-Florida

Curated by ChEMBL
LigandPNGBDBM50246410(2-(3,4-dihydro-2H-chromen-3-yl)-6-(1H-pyrazol-4-yl...)
Affinity DataIC50: 330nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed