BDBM50246427 1-(2-(3,4-dichlorophenoxy)-5-(trifluoromethyl)phenyl)-N-methylmethanamine::CHEMBL507884

SMILES CNCc1cc(ccc1Oc1ccc(Cl)c(Cl)c1)C(F)(F)F

InChI Key InChIKey=VXVOMNFSZSXTSE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50246427   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246427(1-(2-(3,4-dichlorophenoxy)-5-(trifluoromethyl)phen...)
Affinity DataIC50: 21.8nMAssay Description:Inhibition of serotonin reuptake at SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50246427(1-(2-(3,4-dichlorophenoxy)-5-(trifluoromethyl)phen...)
Affinity DataIC50: 1.31E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246427(1-(2-(3,4-dichlorophenoxy)-5-(trifluoromethyl)phen...)
Affinity DataIC50: 1.80E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed