BDBM50246732 3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':4,5,6]pyrrolo[3',4':2,3][1,4] diazepino[1,7-a]indol-2-yl)propyl N-Methylimidothiocarbamate::CHEMBL447317

SMILES CNC(=N)SCCCN1C(=O)C2=C(C1=O)n1ccc3cccc(C4Cc5ccccc5N24)c13

InChI Key InChIKey=RUKXABJVRPYOJF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50246732   

TargetInsulin receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246732(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human INSRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246732(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human CDK2/Cyc2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246732(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human CDK4/CycD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246732(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed