BDBM50247194 9-Fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3Hcyclopenta[a]phenanthrene-17-carboxylic acid [2-(2-{[4-benzylamino-2-hydroxy-4-(2-hydroxy-ethyl)-6-methylheptylcarbamoyl]-methoxy}-ethoxy)-ethyl]-amide::CHEMBL510868

SMILES CC(C)C[C@](CCO)(C[C@H](O)CNC(=O)COCCOCCNC(=O)[C@@]1(O)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)NCc1ccccc1

InChI Key InChIKey=BOCYABOQZPFEMG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247194   

TargetGlucocorticoid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50247194(9-Fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-...)
Affinity DataEC50:  2.50E+3nMAssay Description:Transcriptional activation of Gal4(1-147) tagged glucocorticoid receptor in human HeLa cells by luciferase reporter gene assay relative to OxDex-AEEAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed