BDBM50247195 (8S,9R,10S,11S,13S,14S,16R,17R)-N-(2-(2-(2-(((3S,5R)-2-benzyl-3-(2-hydroxyethyl)-3-isobutylisoxazolidin-5-yl)methylamino)-2-oxoethoxy)ethoxy)ethyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxamide::CHEMBL503957

SMILES CC(C)C[C@]1(CCO)C[C@H](CNC(=O)COCCOCCNC(=O)[C@@]2(O)[C@H](C)C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]23C)ON1Cc1ccccc1

InChI Key InChIKey=NQUHEMYYBHBMEW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247195   

TargetGlucocorticoid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50247195((8S,9R,10S,11S,13S,14S,16R,17R)-N-(2-(2-(2-(((3S,5...)
Affinity DataEC50:  33nMAssay Description:Transcriptional activation of Gal4(1-147) tagged glucocorticoid receptor in human HeLa cells by luciferase reporter gene assay relative to OxDex-AEEAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed