BDBM50247196 (8S,9R,10S,11S,13S,14S,16R,17R)-N-((2R,5R,8R)-1-amino-2-benzyl-5-(hydroxymethyl)-8-isobutyl-1,4,7,10-tetraoxo-12,15-dioxa-3,6,9-triazaheptadecan-17-yl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxamide::CHEMBL452456

SMILES CC(C)C[C@@H](NC(=O)COCCOCCNC(=O)[C@@]1(O)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)N[C@H](CO)C(=O)N[C@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=QWUDSUJGAMQNFE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247196   

TargetGlucocorticoid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50247196((8S,9R,10S,11S,13S,14S,16R,17R)-N-((2R,5R,8R)-1-am...)
Affinity DataEC50:  1.86E+3nMAssay Description:Transcriptional activation of Gal4(1-147) tagged glucocorticoid receptor in human HeLa cells by luciferase reporter gene assay relative to OxDex-AEEAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed