BDBM50247207 2-(biphenyl-4-ylsulfonamido)pentanedioic acid::CHEMBL475540

SMILES OC(=O)CCC(NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(O)=O

InChI Key InChIKey=IQGHPUPMOUUHPP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50247207   

TargetCollagenase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247207(2-(biphenyl-4-ylsulfonamido)pentanedioic acid | CH...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant MMP13 by fluorogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247207(2-(biphenyl-4-ylsulfonamido)pentanedioic acid | CH...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human recombinant MMP8 by fluorogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247207(2-(biphenyl-4-ylsulfonamido)pentanedioic acid | CH...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant MMP13 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247207(2-(biphenyl-4-ylsulfonamido)pentanedioic acid | CH...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant MMP13 by HxBPyne probe-based competitive activity based protein profiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247207(2-(biphenyl-4-ylsulfonamido)pentanedioic acid | CH...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human recombinant MMP9 by fluorogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed