BDBM50247253 CHEMBL473726::N4-benzyl-1-(2-chloro-2-phenylethyl)-N6,N6-dimethyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

SMILES CN(C)c1nc(NCc2ccccc2)c2cnn(CC(Cl)c3ccccc3)c2n1

InChI Key InChIKey=WIVGMFFLXFXBJZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247253   

TargetTyrosine-protein kinase ABL1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50247253(N4-benzyl-1-(2-chloro-2-phenylethyl)-N6,N6-dimethy...)
Affinity DataKi:  160nMAssay Description:Inhibition of human recombinant Abl by filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50247253(N4-benzyl-1-(2-chloro-2-phenylethyl)-N6,N6-dimethy...)
Affinity DataKi:  4.22E+3nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed