BDBM50247418 8-Isopropyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quinazoline-2-carboximidic acid benzyl ester::CHEMBL453129

SMILES CC(C)n1cnc2ccc3nc(sc3c2c1=O)C(=N)OCc1ccccc1

InChI Key InChIKey=KMPXHOHRWCFMTC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50247418   

TargetGlycogen synthase kinase-3 alpha(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50247418(8-Isopropyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quina...)
Affinity DataIC50: 130nMAssay Description:Inhibition of GSK3alpha/betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50247418(8-Isopropyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quina...)
Affinity DataIC50: 150nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50247418(8-Isopropyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quina...)
Affinity DataIC50: 150nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50247418(8-Isopropyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quina...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed