BDBM50247550 4-(5-Bromoindole-3-yl)-6,7-dimethoxyquinazoline::CHEMBL473320

SMILES COc1cc2ncnc(-c3c[nH]c4ccc(Br)cc34)c2cc1OC

InChI Key InChIKey=MWBJNWJINFGNLQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247550   

TargetEpidermal growth factor receptor(Human)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50247550(4-(5-Bromoindole-3-yl)-6,7-dimethoxyquinazoline | ...)
Affinity DataIC50: 131nMAssay Description:Inhibition of human EGFR tyrosine kinase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed