BDBM50247551 4-(5-Chloro-6-fluoroindole-3-yl)-6,7-dimethoxyquinazoline::CHEMBL515401

SMILES COc1cc2ncnc(-c3c[nH]c4cc(F)c(Cl)cc34)c2cc1OC

InChI Key InChIKey=CKNICHHQTFEWGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247551   

TargetEpidermal growth factor receptor(Human)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50247551(4-(5-Chloro-6-fluoroindole-3-yl)-6,7-dimethoxyquin...)
Affinity DataIC50: 209nMAssay Description:Inhibition of human EGFR tyrosine kinase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed